概述
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产品编号 ： SY066 优 |
抗体来源： Mouse |
应用: WB,IHC |
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反应性: H |
MW：147kD(Observed） |
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Western Blot
Western blot analysis of Hela with CD45 mAb diluted at 1:2,000.
产品描述
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蛋白名称 |
CD45 |
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来源 |
Mouse monoclonal antibody is prepared by immunizing synthetic peptide coupled to KLH. |
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特异性 |
The CD45 mouse monoclonal antibody can detect endogenous CD45 proteins. |
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存储 |
Store at -20°C. Stable for one year from the date of shipment. |
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组成 |
1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
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稀释比例 |
WB1:2,000 IHC 1:200 (Optimal dilutions should be determined by the end user) |
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浓度 |
1 mg/ml |
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实测条带 |
147kD |
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克隆性 |
Monoclonal |
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同种型 |
IgG1 |
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别名 |
GP180 antibody, L CA antibody, CD45 antigen antibody |
背景
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CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms which share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions. Antibodies recognising a common epitope on all of the isoforms are termed CD45. |
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