CD68 Mouse mAb(6F3)

产品编号 ： SY073 优

抗体来源： Mouse

应用:  IHC

反应性:   H, M, R

MW：37kD(Observed）

蛋白名称

CD68

来源

Mouse monoclonal antibody is prepared by immunizing synthetic peptide coupled to KLH.

特异性

The CD68 mouse monoclonal antibody can detect endogenous CD68 proteins.

存储

Store at -20°C. Stable for one year from the date of shipment.

组成

1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.

稀释比例

 IHC 1:200

(Optimal dilutions should be determined by the end user)

浓度

1 mg/ml

实测条带

37kD

克隆性

Monoclonal

同种型

IgG1

别名

CD68 antigen antibody, Macrophage antigen CD68 (microsialin) antibody, GP110 antibody

The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells.