CK19 Mouse mAb(11F5)

产品编号 ： SY074 优

抗体来源： Mouse

应用:  IHC

反应性:     H, M, R

MW：44kD(Observed）

蛋白名称

CK19

来源

Mouse monoclonal antibody is prepared by immunizing synthetic peptide coupled to KLH.

特异性

The CK19 mouse monoclonal antibody can detect endogenous CK19 proteins.

存储

Store at -20°C. Stable for one year from the date of shipment.

组成

1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.

稀释比例

 IHC 1:200

(Optimal dilutions should be determined by the end user)

浓度

1 mg/ml

实测条带

44kD

克隆性

Monoclonal

同种型

IgG1

别名

Cytokeratin 19 antibody, Keratin type I cytoskeletal 19 antibody, 40 kDa keratin intermediate filament antibody

This protein is a member of the keratin family. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Keratin 19 is not expressed in hepatocytes, therefore, antibody to keratin 19 is useful in the identification of liver metastasis. The degree of keratin 19 positivity in breast cancer distinguishes malignant from benign tumours. Keratin 19 is often co-expressed with keratin 7.