概述
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产品编号 : SY080 优 |
抗体来源: Mouse |
应用: WB, IHC |
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反应性: H,M,R |
MW:42kD(Observed) |
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Western Blot
Western blot analysis of 1) 293T, 2)Mouse Heart tissue with CDX2 mAb diluted at 1:2,000.
Immunohistochemistry
IHC staining of human rectal cancer tissue with CDX2 mouse mAb(14H6) diluted at 1:200.
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蛋白名称 |
CDX2 |
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来源 |
Mouse monoclonal antibody is prepared by immunizing synthetic peptide coupled to KLH. |
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特异性 |
The CK16 mouse monoclonal antibody can detect endogenous CK16 proteins. |
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存储 |
Store at -20°C. Stable for one year from the date of shipment. |
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组成 |
1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
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稀释比例 |
WB 1:1,000 IHC 1:200 (Optimal dilutions should be determined by the end user) |
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浓度 |
1 mg/ml |
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实测条带 |
54kD |
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克隆性 |
Monoclonal |
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同种型 |
IgG1 |
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别名 |
Caudal type homeo box 2 antibody, Homeobox protein CDX 2 antibody, caudal type homeobox transcription factor 2 antibody |
背景
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CDX2 is a caudal type homeobox gene that encodes an intestine-specific transcription factor that is expressed early in intestinal development and may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. It is expressed in the nuclei of epithelial cells throughout the intestine, from duodenum to rectum. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas and has also been demonstrated in the intestinal metaplasia of the stomach and intestinal-type gastric cancer, while it is not expressed in the normal gastric mucosa. Studies have shown that CDX2 is superior marker compared to CK20.. |
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