概述
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产品编号 ： SY081 优 |
抗体来源： Mouse |
应用: IHC, IF |
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反应性: H, M, R, Fruit Fly, Nematode |
MW：220kD(Observed） |
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Immunohistochemistry
Immunofluorescence Staining of nematode tissue with MYH mouse mAb(11C2) diluted at 1:100. (Provide by Tsinghua University).
Immunohistochemistry
Immunofluorescence double Staining of fruit fly tissue with MYH mouse mAb(11C2)(Green) and F-actin mouse mAb(red) (Provide by NIBS).
产品描述
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蛋白名称 |
Myosin Heavy Chain |
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来源 |
Mouse monoclonal antibody is prepared by immunizing synthetic peptide coupled to KLH. |
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特异性 |
The Myosin Heavy Chain mouse monoclonal antibody can detect endogenous Myosin Heavy Chain proteins. |
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存储 |
Store at -20°C. Stable for one year from the date of shipment. |
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组成 |
1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
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稀释比例 |
IHC 1:200 IF 1:100 (Optimal dilutions should be determined by the end user) |
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浓度 |
1 mg/ml |
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实测条带 |
220kD |
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克隆性 |
Monoclonal |
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同种型 |
IgG1 |
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别名 |
fast skeletal muscle antibody, MYH 3 antibody, HEMHC antibody |
背景
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Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). Cardiac MHC exists as two isoforms in humans, alpha-cardiac MHC and beta-cardiac MHC. These two isoforms are expressed in different amounts in the human heart. During normal physiology, beta-cardiac MHC is the predominant form, with the alpha-isoform contributing around only 7% of the total MHC. Mutations of the MHC genes are associated with several different dilated and hypertrophic cardiomyopathies. |
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