概述
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产品编号 ： SY082 优 |
抗体来源： Mouse |
应用: WB, IHC |
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反应性: R, M |
MW：45kD(Observed） |
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Western Blot
Western blot analysis of Rat Brain Tissue with GFAP mAb diluted at 1:5,000.
Western Blot
Western blot analysis of Mouse Brain Tissue with GFAP mAb diluted at 1:2,000.
IHC
mmunohistochemical analysis of paraffin-embedded Rat Brain Tissue using GFAP（SY082）Mouse mAb diluted at 1:500.
产品描述
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蛋白名称 |
GFAP |
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来源 |
Mouse monoclonal antibody is prepared by immunizing synthetic peptide coupled to KLH. |
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特异性 |
The GFAP mouse monoclonal antibody can detect endogenous GFAP proteins. |
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存储 |
Store at -20°C. Stable for one year from the date of shipment. |
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组成 |
1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
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稀释比例 |
WB 1:2,000-5,000 IHC 1:200-500 (Optimal dilutions should be determined by the end user) |
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浓度 |
1 mg/ml |
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实测条带 |
45kD |
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克隆性 |
Monoclonal |
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同种型 |
IgG1 |
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别名 |
Glial Fibrillary Acidic Protein antibody, Astrocyte antibody, Intermediate filament protein antibody |
背景
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GFAP is a member of the class III intermediate filament protein family. It is heavily, and specifically, expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non myelinating Schwann cells in peripheral nerves. In addition, neural stem cells frequently strongly express GFAP. Antibodies to GFAP are therefore very useful as markers of astrocytic cells. In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes. |
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