CD21 Mouse mAb(2C5)

产品编号 ： SY083 优

抗体来源： Mouse

应用:  IHC

反应性:    H,R, M

MW：113kD(Observed）

蛋白名称

CD21

来源

Mouse monoclonal antibody is prepared by immunizing synthetic peptide coupled to KLH.

特异性

The CD21 mouse monoclonal antibody can detect endogenous CD21 proteins.

存储

Store at -20°C. Stable for one year from the date of shipment.

组成

in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.

稀释比例

IHC 1:200

(Optimal dilutions should be determined by the end user)

浓度

1 mg/ml

实测条带

113kD

克隆性

Monoclonal

同种型

IgG1

别名

Complement C3d receptor antibody, Epstein Barr virus receptor antibody, C3DR antibody

CD21 also known as complement receptor 2 (CR2), C3d receptor or EBV receptor is a 140 kDa protein. CD21 is a glycosylated type I transmembrane protein consisting of an extracellular face of a series of 15 or 16 CCP domains. CD21 is the receptor for complement components C3d and iC3b as well as the Epstein-Barr virus (EBV) glycoprotein gp350/220. The soluble CD21 (sCD21) was shown to efficiently trigger CD23 signalling pathways in human monocytes. By inducing release of proinflammatory cytokines and upregulating expression of molecules involved in antigen presentation, sCD21 modulates critical monocyte functions that may be relevant to allergic and inflammatory disorders.