Ki 67 Mouse mAb(4A8)

产品编号 ： SY087 优

抗体来源： Mouse

应用:  IHC

反应性:   H, M, R

MW： N/A

蛋白名称

Ki 67

来源

Mouse monoclonal antibody is prepared by immunizing synthetic peptide coupled to KLH.

特异性

The Ki 67 mouse monoclonal antibody can detect endogenous Ki 67 proteins.

存储

Store at -20°C. Stable for one year from the date of shipment.

组成

in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.

稀释比例

 IHC 1:200

(Optimal dilutions should be determined by the end user)

浓度

1 mg/ml

实测条带

N/A

克隆性

Monoclonal

同种型

IgG1

别名

Antigen identified by monoclonal antibody Ki 67 antibody, KIA antibody, Proliferation related Ki 67 antigen antibody

Antigen KI-67 is a nuclear protein that is associated with and may be necessary for cellular proliferation. Furthermore it is associated with ribosomal RNA transcription. Inactivation of antigen KI-67 leads to inhibition of ribosomal RNA synthesis. The Ki-67 protein (also known as MKI67) is a cellular marker for proliferation. It is strictly associated with cell proliferation. During interphase, the Ki-67 antigen can be exclusively detected within the cell nucleus, whereas in mitosis most of the protein is relocated to the surface of the chromosomes. Ki-67 protein is present during all active phases of the cell cycle (G1, S, G2, and mitosis), but is absent from resting cells (G0).