概述
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产品编号 ： SY088 优 |
抗体来源： Mouse |
应用: WB, IHC |
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反应性: H, M, R |
MW：92kD(Observed） |
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Western Blot
Western blot analysis of 1) Hela, 2) 293T, 3) MCF7, 4)Mouse Brain tissue ,3) Rat LiverTissue with β-Catenin mAb diluted at 1:2,000.
Immunohistochemistry
IHC staining of human breast cancer tissue with β-Catenin mouse mAb(13C6) diluted at 1:200.
产品描述
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蛋白名称 |
β-Catenin |
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来源 |
Mouse monoclonal antibody is prepared by immunizing synthetic peptide coupled to KLH. |
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特异性 |
The β-Catenin mouse monoclonal antibody can detect endogenous β-Catenin proteins. |
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存储 |
Store at -20°C. Stable for one year from the date of shipment. |
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组成 |
in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
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稀释比例 |
WB 1:1,000 IHC 1:200 (Optimal dilutions should be determined by the end user) |
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浓度 |
1 mg/ml |
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实测条带 |
92kD(Observed） |
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克隆性 |
Monoclonal |
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同种型 |
IgG1 |
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别名 |
CTNNB antibody, Cadherin associated protein antibody, b-catenin antibody |
背景
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The distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and 86 kDa) are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins. Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1 proto oncogene. The central core region of beta catenin is involved in mediation of cadherin catenin complex interaction with EGFR. Beta-Catenin-mediated signalling is involved at several stages of vertebrate neural development. |
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