概述
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产品编号 : SY108 优 |
抗体来源: Mouse |
应用: WB, IHC |
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反应性: H |
MW:118kD(Observed) |
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Western Blot
Western blot analysis of 1) Hela, 2) HepG2,with IDE Mouse mAb diluted at 1:2,000.
Western Blot
Western blot analysis of Hela, HepG2,with IDE Mouse mAb diluted at 1:2,000.
产品描述
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蛋白名称 |
IDE/Insulin Degrading Enzyme |
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来源 |
Mouse monoclonal antibody is prepared by immunizing synthetic peptide coupled to KLH. |
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特异性 |
The IDE mouse monoclonal antibody can detect endogenous IDE proteins. |
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存储 |
Store at -20°C. Stable for one year from the date of shipment. |
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组成 |
in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
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稀释比例 |
WB 1:1,000 IHC 1:200 (Optimal dilutions should be determined by the end user) |
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浓度 |
1 mg/ml |
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实测条带 |
118kD(Observed) |
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克隆性 |
Monoclonal |
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同种型 |
IgG1 |
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别名 |
Abeta-degrading protease antibody, insulin protease antibody, insulinase antibody, insulysin antibody |
背景
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Insulin Degrading Enzyme (IDE) is a large zinc-binding protease of the M16A metalloprotease subfamily known to cleave multiple short polypeptides that vary considerably in sequence. IDE was first identified by its ability to degrade the B chain of the hormone insulin. This activity was observed over fifty years ago, though the enzyme specifically responsible for B chain cleavage was identified more recently. |
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