COX2/Cyclooxygenase 2 Mouse mAb(3D4)

产品编号 ： SY200

抗体来源： Mouse

应用:   IHC

反应性:  H, R, M

MW：74kD(Observed）

蛋白名称

COX2/Cyclooxygenase 2

来源

A Mouse monoclonal antibody is prepared by immunizing synthetic peptide coupled to KLH.

特异性

The COX2/Cyclooxygenase 2 mouse monoclonal antibody can detect endogenous COX2/Cyclooxygenase 2 proteins.

存储

Store at -20°C. Stable for one year from the date of shipment

组成

in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.

稀释比例

IHC 1:100-200

(Optimal dilutions should be determined by the end user)

浓度

1 mg/ml

实测条带

74kD(Observed）

克隆性

Monoclonal

同种型

IgG1

别名

PTGS2 antibody, Prostaglandin H2 synthase 2 antibody, PGHS 2 antibody, Glucocorticoid-regulated inflammatory cyclooxygenase antibody

Prostaglandin-endoperoxide synthase 2, also known as cyclooxygenase-2 or simply COX-2, is an enzyme that in humans is encoded by the PTGS2 gene. There are two isozymes of COX encoded by distinct gene products: a constitutive COX-1 (this enzyme) and an inducible COX-2, which differ in their regulation of expression and tissue distribution. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. A splice variant of COX-1 termed COX-3 was identified in the CNS of dogs, but does not result in a functional protein in humans. Two smaller COX-1-derived proteins (the partial COX-1 proteins PCOX-1A and PCOX-1B) have also been discovered, but their precise roles are yet to be described.