概述
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产品编号 ： SY202 |
抗体来源： Mouse |
应用: IHC |
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反应性: H, R, M |
MW：37kD(Observed） |
|
IHC
Immunohistochemical analysis of paraffin-embedded Human Tonsil Tissue using CD68 （SY202）Mouse mAb diluted at 1:500.
产品描述
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蛋白名称 |
CD68 |
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来源 |
A Mouse monoclonal antibody is prepared by immunizing synthetic peptide coupled to KLH. |
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特异性 |
The CD68 mouse monoclonal antibody can detect endogenous CD68 proteins. |
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存储 |
Store at -20°C. Stable for one year from the date of shipment |
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组成 |
in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
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稀释比例 |
IHC 1:200-500 (Optimal dilutions should be determined by the end user) |
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浓度 |
1 mg/ml |
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实测条带 |
37kD(Observed） |
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克隆性 |
Monoclonal |
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同种型 |
IgG1 |
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别名 |
CD68 antigen antibody, Macrophage antigen CD68 (microsialin) antibody, GP110 antibody |
背景
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The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells. |
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